Phillips NE*, Mandic A*, Omidi S, Naef F†, Suter DM†.
Memory and relatedness of transcriptional activity in mammalian cell lineages. *Equal contribution; †Equal contribution and Corresponding authors
Nature Communications 2019
Raccaud M, Alber AB, Friman ET, Agarwal H, Deluz C, Kuhn T, Gebhardt JCM, Suter DM
Mitotic chromosome binding predicts transcription factor properties in interphase. Corresponding author

Nature Communications 2019


Tidin O, Friman ET, Naef F, Suter DM

Quantitative relationships between SMAD dynamics and target gene activation kinetics in single live cells. Equal contribution and co-corresponding authors

bioRxiv 2018

Alber AB*, Paquet ER*, Biserni M, Naef F, Suter DM. Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates

Molecular Cell 2018, epub August 23

Link to Alber et al.

Nicolas D, Zoller B, Suter DM, Naef F.

Modulation of transcriptional burst frequency by histone acetylation.

PNAS 2018 Jul 3;115(27):7153-7158. doi: 10.1073/pnas.1722330115. Epub 2018 Jun 18.

Callegari A, Sieben C, Benke A, Suter DM, Fierz B, Mazza D, Manley S

Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation.

bioRxiv 2018

Strebinger D, Friman ET, Deluz C, Govindan S, Alber AB, Suter DM. Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions

bioRxiv 2018

Alber AB, Suter DM. Single-Cell Quantification of Protein Degradation Rates by Time-Lapse Fluorescence Microscopy in Adherent Cell Culture.

Journal of Visualized Experiments. 2018 Feb 4;(132). doi: 10.3791/56604.


Delachat AM, Guidotti N, Bachmann AL, Meireles-Filho ACA, Pick H, Lechner CC, Deluz C, Deplancke B, Suter DM, Fierz B. Engineered Multivalent Sensors to Detect Coexisting Histone Modifications in Living Stem Cells.

Cell Chemical Biology 2017 Nov 21. pii: S2451-9456(17)30389-6. doi: 10.1016/j.chembiol.2017.10.008. [Epub ahead of print]

Raccaud M, Suter DM. Transcription factor retention on mitotic chromosomes: regulatory mechanisms and impact on cell fate decisions.

FEBS letter, 2017 Sep 1. doi 10.1002/1873-3468.12828 [Epub ahead of print] Review.

Link to PDF

Mandic A, Strebinger D, Regali C, Phillips NE, Suter DM. A novel method for quantitative measurements of gene expression in single living cells

Methods. 2017 Apr 26. pii: S1046-2023(16)30363-2. doi: 10.1016/j.ymeth.2017.04.008. [Epub ahead of print]    Link to PDF


Deluz C, Strebinger D, Friman ET, Suter DM. The elusive role of mitotic bookmarking in transcriptional regulation: insights from Sox2.
Cell Cycle. 2017 Feb 6:0. doi: 10.1080/15384101.2017.1288332. [Epub ahead of print] Link to PDF


Deluz C, Friman ET, Strebinger D, Benke A, Raccaud M, Callegari A, Leleu M, Manley S, Suter DM. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation.          
Genes & Development 2016 Dec 5. [Epub ahead of print]

Link to PDF


Zhao ZW*, Roy R*, Gebhardt JCM*, Suter DM*, Chapman A, Xie XS. Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy. *Equal contribution
PNAS 2014


Molina N*, Suter DM*†, Zoller B, Gotic I, Naef F†. Stimulus-induced modulation of transcriptional bursting in a single mammalian gene. *Equal contribution; †Corresponding authors
PNAS 2013

Zhao ZW, Gebhardt JC, Suter DM, Xie XS. Reply to “Convergence of chromatin binding estimates in live cells”.
Nature Methods 2013

Gebhardt JCM* Suter DM*, Roy R, Zhao ZW, Chapman A, Basu S, Maniatis T, Xie XS. Probing Transcription Factor DNA Binding at the Single Molecule Level in Live Mammalian Cells. *Equal contribution.
Nature Methods 2013

repository/default/content/sites/suter-lab/files/Gebhardt, Suter et al.pdf


Kern I, Xu R, Julien S, Suter DM, Preynat-Seauve O, Baquié M, Poncet A, Combescure C, Stoppini L, van Thriel C, Krause KH. Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells.
Current Medicinal Chemistry 2012 Dec 10. [Epub ahead of print]

Stratmann M*, Suter DM*, Molina N, Naef F, Schibler U. Circadian Dbp Transcription Relies on Highly Dynamic BMAL1-CLOCK Interaction with E Boxes and Requires the Proteasome. *Equal contribution.
Molecular Cell. 2012 Oct 26;48(2):277-87


Suter DM, Molina N, Naef F, Schibler U. Origins and consequences of transcriptional discontinuity.
Current Opinion in Cell Biology. 2011 Dec;23(6):657-62
Epub 2011 Sep 29.

Saini C, Suter DM, Liani A, Gos P, Schibler U. The Mammalian Circadian Timing System: Synchronization of Peripheral Clocks.
Cold Spring Harbor Symposia in Quantitative Biology. 2011 Dec 16. [Epub ahead of print]

Clément S, Peyrou M, Sanchez-Pareja A, Bourgoin L, Ramadori P, Suter D, Vinciguerra M, Guilloux K, Pascarella S, Rubbia-Brandt L, Negro F, Foti M. Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets.
Hepatology. 2011 Jul;54(1):38-49

Suter DM*, Molina N*, Gatfield D, Schneider K, Schibler U, Naef F. Mammalian genes are transcribed with widely different bursting kinetics. *Equal contribution
Science. 2011 Apr 22;332(6028):472-4


Zhang J, Lu JP, Suter DM, Krause KH, Fini ME, Chen B, Lu Q. Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death.
Experimental Cell Research. 2010 Apr 1;316(6):1070-81


Suter DM, Schibler U. Physiology. Feeding the clock.
Science. 2009 Oct 16;326(5951):378-9.

Suter DM, Preynat-Seauve O, Tirefort D, Feki A, Krause KH. Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells.
Journal of Cellular and Molecular Medicine. 2009 Sep;13(9B):3517-27.

Preynat-Seauve O, Suter DM, Tirefort D, Turchi L, Virolle T, Chneiweiss H, Foti M, Lobrinus JA, Stoppini L, Feki A, Dubois-Dauphin M, Krause KH. Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture.
Stem Cells. 2009 Mar 5;27(3):509-520.

Suter DM, Tirefort D, Julien S, Krause KH. A Sox1 to Pax6 switch drives neuroectoderm to radial glia progression during differentiation of mouse embryonic stem cells.
Stem Cells. 2009 Jan;27(1):49-58.


Suter DM, Krause KH. Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy.
Journal of Pathology. 2008 Aug;215(4):355-68. Review.

Aberdam E, Barak E, Rouleau M, de LaForest S, Berrih-Aknin S, Suter DM, Krause KH, Amit M, Itskovitz-Eldor J, Aberdam D. A pure population of ectodermal cells derived from human embryonic stem cells.
Stem Cells. 2008 Feb;26(2):440-4.


Suter DM, Montet X, Tirefort D, Cartier L, Krause KH. A tetracycline-inducible lentivector system based on EF1-α promoter and native tetracycline repressor allows in vivo gene induction in implanted ES cells.
Journal of Stem Cells. Volume 2 Issue 2, 2007; 63-72.

Radcliffe CM, Arnold JN, Suter DM, Wormald MR, Harvey DJ, Royle L, Mimura Y, Kimura Y, Sim RB, Inogès S, Rodriguez-Calvillo M, Zabalegui N, de Cerio AL, Potter KN, Mockridge CI, Dwek RA, Bendandi M, Rudd PM, Stevenson FK. Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
Journal of Biological Chemistry. 2007 Mar 9;282(10):7405-15.

Suter DM, Dubois-Dauphin M, Krause KH. Genetic engineering of embryonic stem cells.
Swiss Medical Weekly. 2007 Mar 2;137 Suppl 155:36S-38S.


Suter DM, Cartier L, Bettiol E, Tirefort D, Jaconi ME, Dubois-Dauphin M, Krause KH. Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors.
Stem Cells. 2006 Mar;24(3):615-23.


Arnold JN, Wormald MR, Suter DM, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, Sim RB. Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.
Journal of Biological Chemistry. 2005 Aug 12;280(32):29080-7.